Novartis to Build Pharmaceutical Ingredient Plant in North Carolina

It's part of the company's $23 billion investment in U.S. manufacturing.

Three Flags Fly Outside A Novartis Manufacturing Facility
Novartis

Novartis today announced plans to add a new facility in Morrisville, North Carolina, focused on active pharmaceutical ingredient (API) manufacturing for solid dosage tablets, capsules and RNA therapeutics.

This announcement marks the company’s seventh new facility planned within a year of its announced $23 billion investment in U.S.-based manufacturing, research and development. The 56,200-square-foot facility will expand the company’s presence in North Carolina to five facilities across three sites. The infrastructure will support not only today’s medicines, but also the development and delivery of future innovative therapies for US patients.

“Last year we committed to adding seven new facilities in the US, and today we finalize our plans to expand our US manufacturing and R&D footprint in the US,” said Vas Narasimhan, CEO of Novartis. "By building a connected, end-to-end footprint, we are strengthening our ability to locally develop, produce, and deliver medicines at scale, enabling timely access to innovation for patients in the US.”

Since April 2025, Novartis has made progress on its commitment to manufacture all key Novartis medicines for U.S. patients in the U.S. These investments are expanding capacity and building the foundation to deliver advanced therapies to the patients who rely on them, including time-sensitive treatments like radioligand therapies (RLT).

  • February 2026: Broke ground on a new biomedical research center in San Diego, California, expanding its U.S. research presence alongside Cambridge, Massachusetts, and supporting discovery across disease areas including neuroscience and oncology
  • February 2026: Announced a new manufacturing facility in Denton, Texas, to produce RLTs for cancer patients, expanding the company’s coast-to-coast RLT network to five facilities
  • January 2026: Announced a new RLT manufacturing facility for cancer treatments in Winter Park, Florida, the first in the Southeastern U.S.
  • December 2025: Broke ground on a flagship manufacturing hub in North Carolina, adding solid dosage tablet and capsule and biologics production and packaging for treatments across oncology, immunology, neuroscience, and cardiovascular, renal and metabolic diseases
  • November 2025: Opened a new RLT manufacturing facility for cancer treatments in Carlsbad, California – the first such site in the region serving the Western US, Alaska, and Hawaii
  • Ongoing: Expansions of existing RLT facilities in Indianapolis, Indiana, and Millburn, New Jersey, supporting current and future demand for these cancer treatments
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